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Secure solutions to alcohol problems, GWU Medical Center1 Substance Abuse and Mental Health Services Administration .The primary objective of of this study was a confirmation that tibolone decreases the risk of osteoporotic vertebral fractures. Which secondary objectives were to evaluate effects of tibolone on the risks of the non-vertebral fractures, cancer, deep vein thrombosis and cardiovascular diseases through of the study of the study. There have significantly reduction in by vertebral fractures, of 70 instances in the treated group versus 126 cases per 1000 person-years in the placebo group – .
– the only relevant detrimental effect been a increased risk of stroke, in women were over the age 70 it should be used with caution in elderly women tibolone is, when the potential benefits deriving / risk profile can be lower than for younger women beneath the age of 70 years -.