The gravity is only a single case , a public health concern. Yellow fever is in the tropical regions of Africa and South America, where 44 countries as at – risk are endemic. The threat to public health from the disease is removed only when vaccination rates in vulnerable areas are at least 60-80 percent. Currently, 610 million people are as at – risk of the disease in Africa.
The 12 countries participating in the Yellow Fever Initiative are Benin, Burkina Faso, Cameroon, C te d’Ivoire, Liberia, Nigeria, Senegal, Sierra Leone and Togo?The Ministries of Health of these 12 countries are supported financially and technically by a Yellow Fever launched in February launched in February 2006 with the WHO and now, M decins Sans Fronti res, comprises the Association pour? decin Pr? Preventive , the Programme for Appropriate Technology , the European Union ‘s Humanitarian Aid Office , the United States Centers for Disease Control and Prevention , The Global Outbreak Alert and Response Network and the Institut Pasteur.Geiger and his colleagues have of therapeutic goals that would raise stem cell mobilization looking -. You are working with specially bred mouse in her research because a large proportion of current knowledge about cellular and molecular regulation of G-CSF – induced stem cell is from mouse trials. Since the G-CSF process which hematopoietic stem and progenitors mobilized by evolutionary between mice and humans contains a preservative, inbred mouse strains be valuable replace studies which can be translated as to humans..
Works from their been published research findings, the scientists were able track a region on chromosome 11 Add Your your mouse models which regulates G-CSF – induced mobilization of blood stem cells. Of 12 genes positioned in this area is, pointed on Egfr tests in the initiation in the triggering molecular reactions growth the growth, the Dr. Geiger the proliferation and migrate is involved. Mutations to Egfr have been cancer.
In one bed – side to bench approach, a researcher at Cincinnati Children’s Hospital Medical Centre reporting at Nature Medicine that pharmacologically inhibition of one signaling by EGFR raised increase mobilization of hematopoietic stem cells on mice.