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Since the clinical program started in 2013, two Phase I trials have been completed in healthy volunteers and obese/obese subjects. The total results indicate that AZP-531 was well tolerated, with improved glucose control and reduced weight in obese topics over a two-week treatment period. The program is in Phase II clinical development for the treatment of Prader-Willi syndrome and in Stage Ib for type 2 diabetes.. Detailed data will be offered from the two Phase I trials carried out in 76 healthy volunteers and obese or obese subjects. Top-series data released end of 2014 indicated an excellent basic safety profile, a pharmacokinetic profile in keeping with once-a-time administration and positive effects on glucose control and on body weight of obese subjects.