Large-scale replication studies are required to confirm this finding and to improve the precision of our estimates.?.. Alcohol may increase blood circulation pressure to a much greater level than previously thought Previous observational studies have reported that heavy alcohol intake is certainly a risk factor for hypertension but such studies may be confounded by factors such as diet, smoking, exercise levels and socio-economic position. Scientific trials exploring the link are tough to implement and have limited follow-up period. The Bristol research, led by Dr Sarah Lewis of the University’s Department of Social Medication, took a different strategy focused on individuals who have a mutation on a gene which affects their body’s ability to eliminate alcoholic beverages.ASA's PSH is a patient-centered, physician-led, team-based practice model of coordinated care and attention that guides a patient throughout the entire surgical experience. The collaborative is supposed to bring health care organizations to develop together, pilot, and assess this innovative model to boost care for surgical patients from the moment surgery is planned, through discharge and recovery from a medical facility and beyond.