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Two research showed an increased risk of uterine fibroids with DES exposure33,34; another showed increased dangers of endometriosis and depression however, not fibroids.35,36 Our research did not assess the dangers of the conditions in association with DES publicity, but we previously reported no significant increase in the risk of fibroids or the risk of melancholy among DES-exposed women in comparison with the risk among unexposed females.32,37 A recently available study of malignancy risk in a DES-exposed Dutch human population reported no significant increase in the risk of breast cancer as compared with the risk in the general inhabitants.38 The discrepancy between this observation and our findings could be related to differences in research design, chance, or perhaps the DES dose; in our study, excess risk was seen primarily among females with vaginal epithelial changes, a condition not really assessed in the Dutch research.The data will be presented during the Retina: Dry out AMD portion of the ISOPT plan on Saturday, December 5, 2009 at 10:20 a.m. CET in Hall A of the Rome Cavalieri Hilton. Related StoriesDrug used to treat Parkinson's and related diseases may delay or prevent macular degenerationResearchers discover that vitamin D may play significant part in preventing AMD among womenAllergan signs licensing contract with Mimetogen to build up, commercialize tavilermide for treatment of dry out eyesight diseaseNancy Boman, M.D., Ph.D.