The transaction is likely to close in the second half of 2011 also to end up being neutral to Aetna’s financial outcomes in 2011 and 2012. ‘This acquisition matches well with Aetna’s primary business, which has a strong focus on consumer-directed item offerings,’ said Tag T. Bertolini, chairman, CEO and president. ‘With an increased focus on consumerism, the acquisition of PayFlex will prolong Aetna’s ability to provide associates with flexible, customized, easy-to-use tools and answers to better manage their health care expenses.’ Joseph M.There have been no notable variations between either ticagrelor dosage group and placebo in the prices of renal or bradyarrhythmic adverse events; however, adverse occasions of gout were significantly more regular with ticagrelor than with placebo . Rates of overall adverse events, serious adverse occasions, and noncardiovascular factors behind death are listed in Table S2 in the Supplementary Appendix. Discussion Patients who have had a myocardial infarction remain at heightened risk for ischemic events over the long term.3-5 In the PEGASUS-TIMI 54 trial, the addition of the P2Y12 receptor antagonist ticagrelor to low-dosage aspirin in patients 1 to three years after a myocardial infarction significantly reduced the chance of cardiovascular loss of life, myocardial infarction, or stroke.