If a couple is normally having sex and the condom slips or breaks off, if a diaphragm or cervical cap slips out of place, or if a girl forgot to take her contraceptive pills for 2 times in a row, a woman may choose to consider using crisis contraception. It is also open to young women who are pressured to have unprotected sex. Emergency contraception is not recommended for females who all know they are pregnant. How Is Emergency Contraception Available? Emergency contraceptive pills are currently offered by drug stores or family members planning clinics for anyone 17 or older without a prescription. Younger teens can only get ECPs with a doctor’s prescription. Lately, the FDA approved one make of ECPs to be sold over-the-counter without a age or prescription requirement.All the authors attest to the accuracy and completeness of the info reported and the adherence of the analysis to the protocol, and all of the decision was made by the authors to post the manuscript for publication. The protocol, including the statistical analysis program, is offered by NEJM.org. Dosage Escalation and Cohort Growth The study was initially planned to evaluate the concurrent regimen with the use of a standard 3+3 design for the dose-escalation phase, followed by cohort expansion to a total of up to 16 patients at the maximum doses that were associated with an acceptable degree of adverse events or the maximum administered dose.